[中文簡歷 Chinese CV]                   [英文簡歷 English CV]

張偉嶠 教授 臺北醫學大學 臨床藥物基因體學暨蛋白質體學碩士學位學程 主任 臺北醫學大學 藥學系 臨床藥學科 高雄醫學大學 臨床醫學研究所 台灣藥學會 秘書長 專長：免疫基因組學、藥物基因體學、鈣離子通道

學校經歷
1. 英國牛津大學 / 生理解剖暨遺傳所 (博士)
2. 國立成功大學 / 藥理學研究所 (碩士)
3. 臺北醫學大學 / 藥學系 (大學)

工作經歷
1. 臺北醫學大學藥學系臨床藥學科 / 副教授
2. 高雄醫學大學醫學系醫學遺傳學科 / 助理教授
3. 高雄醫學大學研究資源整合中心 / 組長
4. 日本理化學研究所(RIKEN) SNP研究中心 / 研究員
5. 日本早稻田大學 先端生命醫科學中心 / 訪問學者
6. 衛生署 藥政處 / 副審查員

關鍵論文

STIM1 Overexpression Promotes Colorectal Cancer Progression, Cell Motility and COX-2 Expression.
Wang JY, Sun J, Huang MY, Wang YS, Hou MF, Sun Y, He H, Krish-na N, Chiu SJ, Lin S, Yang S*, Chang WC*.
Oncogene. 2015 ;34, 4358–4367.(published online 10 November 2014)

STIM1- and Orai1-mediated Ca(2+) oscillation orchestrates invadopodium formation and melanoma invasion.
Sun J, Lu F, He H, Shen J, Messina J, Mathew R, Wang D, Sarnaik AA, Chang WC, Kim M, Cheng H, Yang S.
J Cell Biol. 2014 Nov 24;207(4):535-48.[Epub 2014 Nov 17]

Involvement of Intracellular Calcium Mobilization in IL-8 Activation in Human Retinal Pigment Epithelial Cells.
Yang IH, Wong JH, Chang CM, Chen BK, Tsai YT, Chen WC, Wang ET, Hsu WL, Chang WC
Invest Ophthalmol Vis Sci. 2015 Jan 15;56(2):761-9.

PTX3 gene activation in EGF-induced head and neck cancer cell metastasis.
Chang WC, Wu SL, Huang WC, Hsu JY, Chan SH, Wang JM, Tsai JP, Chen BK.
Oncotarget. 2015 Apr 10;6(10):7741-57.

Translocation of NF-κB and expression of cyclooxygenase-2 are enhanced by ketamine-induced ulcerative cystitis in rat bladder.
Juan YS, Lee YL, Long CY, Wong JH, Jang MY, Lu JH, Wu WJ, Huang YS, Chang WC, Chuang SM.
Am J Pathol. 2015 Aug;185(8):2269-85.

Correlation of clinical features and genetic profiles of stromal interaction molecule 1 (STIM1) in colorectal cancers.
Wong HS, Chang WC.
Oncotarget. 2015 Dec 8;6(39):42169-82.

Integrative bioinformatic analyses of an oncogenomic profile reveal the biology of endometrial cancer and guide drug discovery.
Wong HS, Juan YS, Wu MS, Zhang YF, Hsu YW, Chen HH, Liu WM, Chang WC.
Oncotarget. 2016 Feb 2;7(5):5909-23.

Characterization of cytokinome landscape for clinical responses in human cancers.
Wong HS, Chang CM, Liu X, Huang WC, Chang WC.
Oncoimmunology. 2016 Nov 4;5(11):e1214789.

Prediction for Intravenous Immunoglobulin Resistance by Using Weighted Genetic Risk Score Identified From Genome-Wide Association Study in Kawasaki Disease.
Ho-Chang Kuo, Henry Sung-Ching Wong, Wei-Pin Chang, Ben-Kuen Chen, Mei-Shin Wu, Kuender D. Yang, Kai-Sheng Hsieh, Yu-Wen Hsu, Shih-Feng Liu, Xiao Liu, Chang WC.
Circulation.Cardiovascular genetics. 2017 Oct 1(5). pii: e001625.

Losses of cytokines and chemokines are common genetic features of human cancers: the somatic copy number alterations are correlated with patient prognoses and therapeutic resistance.
Wong HS, Chang WC.
Oncoimmunology.2018 Jul 30.(7):e1468951

Functional Effects of let-7g Expression in Colon Cancer Metastasis.
Chang CM^#, Wong HS^#, Huang CY^#, Hsu WL, Maio ZF, Chiu SJ, Tsai YT, Chen BK, Wan YY, Wang JY^*, Chang WC*.
Cancers (Basel). 2019 April 6.

Meta-analysis of genome-wide association studies identifies three loci associated with stiffness index of the calcaneus.
Hsing-Fang Lu, Kuo-Sheng Hung, Hou-Wei Chu, Henry Sung-Ching Wong, Jihye Kim, Bo Youl Choi, Mi Kyung Kim, Yu-Ting Tai, Shiro Ikegawa, Er-Chieh Cho, Chang WC.
Journal of Bone and Mineral Research. 2019 Feb 19.